+ MAP: SUBURBS AT RISK OF FLOODING ON WEDNESDAY
+ FLOODS WILL BE WORSE THAN '74: BLIGH
Authorities have called for calm as Brisbane's roads clog up with workers seeking to flee the city while the Brisbane River breaches its banks at multiple locations.
Today, Lord Mayor Campbell Newman warned the worst of the flooding was yet to come, with Thursday likely to be "devastating".
Cr Newman said latest flood modelling suggested 6500 properties could be inundated, with 16,500 to be partially affected.
Police advised there have been no forced evacuations in the CBD, however numerous employers have advised their workers to go home, including department stores Myer and David Jones in the Queen Street Mall.
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Public transport will continue to operate throughout the afternoon, however Translink advises of service cancellations, disruptions and diversions in place across the network due to flooding.
Deputy Mayor Graham Quirk called for residents to remain clear-headed.
The Brisbane River laps at the Riverside Centre in Brisbane's CBD. CLICK ON THE IMAGE TO SEE MORE PHOTOS
"People need to be sensible and not panic, but they need to be prepared," Cr Quirk said.
"What we've seen today is a fair bit of panic. We've had a significant departure of people from the CBD going back to their homes."
An evacuation centre has been set up at the RNA Showgrounds at Bowen Hills for residents affected by floods.
A Brisbane City Council statement said the centre had been set up for those who wanted to evacuate of their own accord and