Brumbies coach Andy Friend yesterday named prop Dan Palmer, No 8 Ita Vaea and winger Henry Speight in his starting XV.
Inside centre Robbie Coleman, who earned one cap in 2010, will make his starting debut as Adam Ashley-Cooper centre partner.
Flyhalf Matt Giteau will lead the team in what will be openside flanker Julian Salvi's 50th match.
The Brumbies team:
1. Ben Alexander, 2. Stephen Moore, 3. Dan Palmer, 4. Ben Hand, 5. Mark Chisholm, 6. Mitch Chapman, 7. Julian Salvi, 8. Ita